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Renal and Cardiovascular Effects of Terlipressin in Patients with Cirrhosis and Ascites - Article


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General Topics A-Z

Cirrhosis

Cirrhosis (Primary Biliary); Cirrhosis of the Liver; Liver Cirrhosis 



Clinical Trial: Renal and Cardiovascular Effects of Terlipressin in Patients with Cirrhosis and Ascites

This study is currently recruiting patients.

Sponsored by: Hvidovre University Hospital
Information provided by: Hvidovre University Hospital

Purpose

The purpose of this study is to investigate the effect of terlipressin on myocardial perfusion and renal function.

Hypothesis: Significant improvement of renal function reflected by: glomerular filtration rate (GFR), renal blood flow (RBF), excretion of salt and metabolites in the urine and related hormones and peptides in the blood. No effect on the systolic function of the heart.

Condition Intervention Phase
Cirrhosis
Ascites
  Drug: Terlipressin
 Phase II
Phase III

MedlinePlus consumer health information 

Study Type: Interventional
Study Design: Randomized, Double-Blind, Placebo Control, Crossover Assignment, Efficacy Study

Eligibility

Ages Eligible for Study:  18 Years   -   75 Years,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Cirrhosis and ascites

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00115947


Denmark, Hvidovre
      Hvidovre Hospital, Copenhagen,  Hvidovre,  2650,  Denmark; Recruiting
Aleksander Krag, MD  36323181    aleksander.krag@hh.hosp.dk 
Aleksander Krag Krag, MD,  Principal Investigator

Study chairs or principal investigators

Aleksander Krag Krag, MD,  Principal Investigator,  Hvidovre Hospital   

More Information

Study ID Numbers:  2004-000568-29
Record last reviewed:  June 2005
Last Updated:  June 30, 2005
Record first received:  June 26, 2005
ClinicalTrials.gov Identifier:  NCT00115947
Health Authority: Denmark: Danish Medicines Agency
ClinicalTrials.gov processed this record on 2005-07-05


Source: ClinicalTrials.gov
Cache Date: July 6, 2005

Resources



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November 30, 2009


Page Updated: October 15, 2009
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