Clinical Trial: ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence

This study is currently recruiting patients.

Sponsors and Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of California, San Francisco
Information provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Purpose

This study consists of two studies with overlapping cohorts. One is a follow up epidemiological study of urinary incontinence, the other is a case control study of lower urinary tract dysfunction in women with diabetes.

Study One: Subjects for the study will be a retrospective cohort of 2100 middle-aged and older women from a large health maintenance organization who have participated in the Reproductive Risk Factor for Incontinence Study at Kaiser (RRISK). The RRISK I study assembled a retrospective cohort of long-term female Kaiser Permanente members to determine the association between specific childbirth events, hysterectomy, hormone use and urinary incontinence later in life. The study also provides descriptive information on urinary incontinence by type, age, ethnicity, severity and age of onset.

Study Two: Women with diabetes have a 30-70% increased risk of lower urinary tract dysfunction, including lower urinary tract symptoms, urinary incontinence, and ultimately bladder cystopathy. This sudy investigates the natural history, risk factors, and possible mechanisms of lower urinary tract dysfunction and infection among women with type 2 diabetes as compared to women without diabetes.

Condition
Urinary Incontinence
Diabetes

MedlinePlus related topics:  Diabetes;   Urinary Incontinence

Study Type: Observational
Study Design: Natural History, Longitudinal, Defined Population, Retrospective/Prospective Study

Further Study Details: 

Expected Total Enrollment:  2350

Study start: July 2003

Eligibility

Ages Eligible for Study:  44 Years   -   73 Years,  Genders Eligible for Study:  Female

Accepts Healthy Volunteers

Criteria

  • Previous participation in the Reproductive Risk Factors for Incontinence Study at Kaiser.
  • Women aged 40-69 on 1/1/99 who have been Kaiser Permanente members since age 18 and have had half or more of their deliveries at Kaiser Permanente or are nulliparous and have diabetes.

Location and Contact Information


California
      Kaiser Permanente, Northern California, Division of Research, Oakland,  California,  94612,  United States; Recruiting
Arona Ragins, M.A.  510-891-3748 

More Information

Study ID Numbers:  ORSCOR
Record last reviewed:  October 2004
Last Updated:  October 14, 2004
Record first received:  September 24, 2003
ClinicalTrials.gov Identifier:  NCT00069368
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005