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Clinical Trial: Pilot Study of Curcumin (Diferuloylmethane Derivative) With or Without Bioperine in Patients with Multiple Myeloma

This study is currently recruiting patients.

Sponsored by: M.D. Anderson Cancer Center
Information provided by: M.D. Anderson Cancer Center


The purpose of this study is to examine the response to treatment with curcumin with or without bioperine in patients with multiple myeloma.
Condition Intervention
Multiple Myeloma
 Drug: Curcumin
 Drug: Bioperine

MedlinePlus related topics:  Multiple Myeloma

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Dose Comparison, Safety/Efficacy Study

Further Study Details: 
Primary Outcomes: To evaluate clinical tolerance and safety in the two arms: curcumin versus curcumin plus Bioperine
Expected Total Enrollment:  24

Study start: November 2004


Genders Eligible for Study:  Both

Inclusion Criteria:

Exclusion Criteria:

  • Previously untreated patients with high tumor mass; symptomatic or impending fractures.
  • Patients with significant cardiac disease.
  • Patients with comorbid condition which renders patients at high risk of treatment complications.
  • History of significant neurological or psychiatric disorders.

Location and Contact Information

Please refer to this study by identifier  NCT00113841

Gracy Zachariah, RN      713-792-2669 

      UT MDAnderson Cancer Center, Houston,  Texas,  77030,  United States; Recruiting
Gracy Zachariah, RN  713-792-2669 

Study chairs or principal investigators

Saroj Vadhan-Raj, MD,  Principal Investigator

More Information

Study ID Numbers:  2003-0436
Record last reviewed:  June 2005
Last Updated:  June 30, 2005
Record first received:  June 10, 2005 Identifier:  NCT00113841
Health Authority: United States: Food and Drug Administration processed this record on 2005-07-05

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