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All Topic Areas 1 - 10 of 53  more >> Genes and Gene Therapy Human Genome Project BRCA CF Gene Mutation Apolipo-protein E (apoe) Gene Cystic Fibrosis Cystic Fibrosis Research Directions CF Fibrocystic Disease of Pancreas Mucoviscidosis Articles 1 - 5 of 20  more >> Schizophrenia Gene Variant Linked to Risk Traits Researchers at the NIH's National Institute of Mental Health (NIMH) have identified a relationship between a small section of one gene, the brain chemical messenger glutamate, and a collection of traits known to be associated with schizophrenia. The finding confirms the gene responsible for management of glutamate is a promising candidate in determining risk for schizophrenia. The study, conducted by Michael Egan, M.D., Daniel Weinberger, M.D., and colleagues, will be in the August 24th issue... National Institutes of Health Gene Therapy for Cancer: Questions and Answers Key Points Gene therapy is an experimental treatment that involves introducing genetic material into a person’s cells to fight disease (see Question 2). Researchers are studying gene therapy for cancer through a number of different approaches (see Question 3). A gene can be delivered to a cell using a carrier known as a “vector.” The most common types of vectors used in gene therapy are viruses (see Question 4). The viruses used in gene therapy are altered to make them safe;... Mutant Gene Linked to Obsessive Compulsive Disorder Analysis of DNA samples from patients with obsessive compulsive disorder (OCD) and related illnesses suggests that these neuropsychiatric disorders affecting mood and behavior are associated with an uncommon mutant, malfunctioning gene that leads to faulty transporter function and regulation. Norio Ozaki, M.D., Ph.D., and colleagues in the collaborative study explain their findings in the October 23 Molecular Psychiatry. Researchers funded by the National Institutes of Health have found a... National Institutes of Health Study Reveals Patterns of Gene Activity in the Mouse Nervous System The first published data from a government-funded project provide remarkable new insights into where specific genes are active in the mouse nervous system during development and adulthood. Information from this project will advance researchers' understanding of how particular genes function in the brain and spinal cord, leading to insights about how the nervous system works. It also may lead to new ways of preventing or treating disorders such as Parkinson's disease, Alzheimer's, psychiatric... National Institutes of Health Gene Hunting Many years of research have demonstrated that vulnerability to mental illnesses—such as schizophrenia, bipolar disorder, early-onset depression, anxiety disorders, autism, and attention deficit hyperactivity disorder—has a genetic component. It is now clear that these disorders are not due to a single defective gene, but to the joint effects of many genes acting together with nongenetic factors.1,2,3 Despite the daunting complexity, progress is being made. Researchers are hunting genes... National Institute of Mental Health News 1 - 5 of 1862  more >> Genes And Genius: Researchers Confirm Association Between Gene And Intelligence ScienceDaily - Tue, 27 Feb 2007 04:00 EST Gene Glitch May Up Early Heart Disease WebMD - Thu, 01 Mar 2007 12:00 EST Gene therapy may help with diseased limbs The Earth Times - Wed, 28 Feb 2007 04:58 EST Gene Glitch May Up Early Heart Disease WebMD - Thu, 01 Mar 2007 11:44 EST Gene Therapy Shows Promise As Treatment For Diseased Limbs MedicalNewsToday - Fri, 02 Mar 2007 11:00 EST Clinical Trials 1 - 5 of 329  more >> Vaccine Therapy and Detection of Immunologic Responses with Tumor Specific Mutated RAS Peptides in Adult Cancer Patients with Solid Tumors ClinicalTrials.gov Identifier: NCT00001380 - Completed Neoplasm Vaccine Therapy with Tumor Specific Mutated RAS Peptides and IL-2 or GM-CSF for Adult Patients with Solid Tumors ClinicalTrials.gov Identifier: NCT00001581 - Completed Colonic Neoplasm; Lung Neoplasm; Neoplasm; Pancreatic Neoplasm; Thyroid Neoplasm A Phase I/II Trial of Vaccination with Mutant Ras Peptide Pulsed Dendritic Cells in the Treatment of HLA A2.1 Positive Patients with Colorectal Cancer ClinicalTrials.gov Identifier: NCT00001794 - Recruiting Colorectal Neoplasm; Neoplasm Metastasis Phase I Pilot Study of Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer ClinicalTrials.gov Identifier: NCT00004471 - Active, not recruiting Cystic Fibrosis Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) with Advate (FLrFVIII) in Hemophilia A ClinicalTrials.gov Identifier: NCT00141843 - Active, not recruiting Hemophilia A

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