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  • Hydroxyurea Therapy Improves Survival in Most Severely Affected Sickle Cell Patients
    Sickle cell anemia patients who took the drug hydroxyurea over a 9-year period experienced a 40 percent reduction in deaths, according to the first study to evaluate whether the treatment prolongs life, announced the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. The study of 299 adult sickle cell patients with moderate to severe forms of the disease, found that improved survival was related to the benefits associated with hydroxyurea treatment — an...
    National Institutes of Health
  • Gene Therapy for Cancer: Questions and Answers
    Key Points Gene therapy is an experimental treatment that involves introducing genetic material into a person’s cells to fight disease (see Question 2). Researchers are studying gene therapy for cancer through a number of different approaches (see Question 3). A gene can be delivered to a cell using a carrier known as a “vector.” The most common types of vectors used in gene therapy are viruses (see Question 4). The viruses used in gene therapy are altered to make them safe;...

  • Small Trial Shows Daclizumab Add-On Therapy Improves Multiple Sclerosis Outcome
    A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements. The trial was led by investigators at the National Institute of Neurological Disorders and Stroke (NINDS), a component of the...
    National Institutes of Health
  • Photodynamic Therapy for Cancer: Questions and Answers
    What is photodynamic therapy? Photodynamic therapy (PDT) is a treatment that uses a drug, called a photosensitizer or photosensitizing agent, and a particular type of light. When photosensitizers are exposed to a specific wavelength of light, they produce a form of oxygen that kills nearby cells (1, 2, 3). Each photosensitizer is activated by light of a specific wavelength (3, 4). This wavelength determines how far the light can travel into the body (3, 5). Thus, doctors use specific...

  • Adjuvant Therapy for Breast Cancer: Questions and Answers
    Researchers have been studying breast cancer for many years to learn how best to treat this disease. They have given special attention to ways to prevent breast cancer from recurring (returning) after primary treatment. Scientists once thought that breast cancer metastasizes (spreads) first to nearby tissue and underarm lymph nodes before spreading to other parts of the body. They now believe that cancer cells may break away from the primary tumor in the breast and begin to metastasize even...

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November 23, 2009



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