Clozapine (trade names Clozaril®; Leponex®), approved by the FDA in 1989, was the first of the atypical antipsychotics. Clozapine is the only FDA approved medication indicated for treatment-resistant schizophrenia and for reducing the risk of suicidal behaviour in patients with schizophrenia.
Barbiturate intoxication and overdose as related to Clozapine
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