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Quetiapine as related to Apert syndrome


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Seroquel 

Acrocephalosyndactyly (Apert); Acrocephaly 

Quetiapine (kwe-TYE-a-peen), marketed by AstraZeneca with the brand name Seroquel, is one of the atypical antipsychotics. Quetiapine has FDA and international approvals for the treatment of schizophrenia and acute mania in bipolar disorder. It is used "off-label" to treat other disorders, such as post-traumatic stress disorder, obsessive compulsive disorder, and as a sedative for those with sleep disorders.

Apert syndrome is a genetic disorder characterized by the premature fusion of certain bones of the skull (craniosynostosis), which prevents further growth of the skull and affects the shape of the head and face. In addition, a varied number of fingers and toes are fused together (syndactyly). Many of the characteristic facial features of Apert syndrome result from the premature fusion of the skull bones. The head is unable to grow normally, which leads to a sunken appearance in the middle of t...


Quetiapine as related to Apert syndrome


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November 23, 2009



Page Updated: January 17, 2009
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