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Lactulose as related to Alpha-1 Antitrypsin Deficiency


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Cephulac; Cholac; Chronulac; Constilac; Constulose; Duphalac; Enulose 

AAT; alpha-1 proteinase inhibitor; alpha-1 related emphysema; genetic emphysema; hereditary pulmonary emphysema; inherit... 

Lactulose is a synthetic sugar used in the treatment of liver disease and constipation. Lactulose absorbs ammonia (produced in liver disease) from the bloodstream through the intestinal wall. In the treatment of chronic constipation it draws water into the bowel, softening the stool. It consists of monosaccharides fructose and galactose.

Alpha-1 is an inherited disorder that may result in you developing a serious lung/ liver disease and passing the defective AAT gene onto your children. An estimated 100,000 people in the U.S. and a similar number in Europe are estimated to have the severe deficiency. In normal individuals large amounts of alpha-1 antitrypsin (AAT) is made in the liver and released into the blood. In AAT deficient individuals, the AAT made in the liver cannot be fully released into the blood.


Lactulose as related to Alpha-1 Antitrypsin Deficiency


  • Alpha-1 Advocacy Alliance - Liver Cirrhosis and Transplatation
    Testing for AAT Deficiency. Alpha One International Registry. Issues in Cirrhosis ... Lactulose also acts as an osmotic agent, decreasing intestinal transit time. ...

  • Liver Cirrhosis - Surgery abroad with Globe Health Tours.
    Lactulose decreases the production of ammonia in the gut and also its ... Alpha 1 Antitrypsin Deficiency. Liver Cancer. Glossary Of Liver Transplantation Terms ...

  • Cirrhosis - Ask Dr Wiki
    Alpha 1-antitrypsin deficiency (AAT). Autosomal recessive disorder. ... Laxatives, such as lactulose, decrease risk of constipation; their role in ...

  • Acne
    ... Wilson's disease, alpha-1-antitrypsin deficiency and others, binary ... encephalopathy with lactulose and/or antibiotics, treatment of upper ...

  • AccessMedicine | Cirrhosis
    Topics Discussed: alpha 1-antitrypsin deficiency; anemias; ascites; bile duct ... syndrome; hypertension, portal; hypoprothrombinemias; lactulose; liver cirrhosis; ...

  • JCI - Issue 84(4)
    With low or moderate doses of lactulose, stool water losses were reduced by as ... A lpha 1-Antitrypsin (alpha 1AT) deficiency is characterized by insufficient ...

  • Cirrhosis
    ... such as hemachromatosis, Wilsons disease, and alpha-1 antitrypsin deficiency ... The laxative lactulose is given as a syrup or enema is given to empty the bowels ...

  • the Drug Monitor - Post-Operative Nursing Care for the Liver ...
    Alpha 1 Antitrypsin Deficiency: a1-antitrypsin is an inhibitor of trypsin, an ... Administer lactulose and/or neomycin as ordered to treat high serum ammonia levels. ...

  • Channel Management System- Washington, DC
    ... such as hemachromatosis, Wilson's disease, and alpha-1 antitrypsin deficiency ... The laxative lactulose is given as a syrup or enema is given to empty the bowels ...

  • Kristalose (lactulose) for children / kids - (Medications ...
    GI for Kids is East Tennessee's premier pediatric ... Alpha-1-Antitrypsin Deficiency. Anorexia Anorexia. Barrett's Esophagus Barrett's Esophagus ...

  • Indian Pediatrics - Editorial
    ... Wilson's disease and alpha-1 antitrypsin deficiency were excluded by appropriate ... were started for AP and lactulose, gentamicin and L-Dopa for heptatic ...

  • BARC DISEASE DEFINITIONS
    18. Alpha-1-Antitrypsin deficiency .18. Galactosemia.18. Hereditary Fructose Intolerance. ... after an initiation of treatment with lactulose or cathartics ...

  • Cirrhosis - Adventist HealthCare
    ... such as hemachromatosis, Wilson's disease, and alpha-1 antitrypsin deficiency ... The laxative lactulose is given as a syrup or enema is given to empty the bowels ...

  • Texas Liver Coalition
    Alpha-1 Antitrypsin Deficiency ... The accumulation of misfolded alpha-1 antitrypsin molecules in the liver can ... Lactulose ...

  • Index
    alpha-1 antitrypsin deficiency (AAD), 140–152. cigarette smoking and, 146, 149, 151t ... lactulose, 229. lamivudine (LAM) for chronic HBV, 30, 31, 32, 69t, 70 ...

  • Cirrhosis - wikidoc
    Alpha-1 Antitrypsin Deficiency. Autoimmune cholangiopathy. Autoimmune hepatitis ... Laxatives, such as lactulose, decrease risk of constipation; their role in ...

  • HIGH-YIELD F ACTS Gastroenterology
    Lactulose for hepatic encephalopathy (broken down by colonic bacteria. and causes NH ... Alpha-1-antitrypsin. deficiency. Hemochromatosis. A patient with alcoholic ...

  • Curbside Consultation of the Liver: 49 Clinical Questions
    ... my patient who is a carrier for alpha-1-antitrypsin deficiency? ... My Patient Who Is a Carrier for Alpha-1-Antitrypsin Deficiency? ... Much Lactulose Should I ...

  • cirrhosis - definition of cirrhosis in the Medical dictionary ...
    ... lactulose to decrease pH in the intestines, and administering antibiotics to ... Wilson's disease, alpha-1-antitrypsin deficiency, intestinal bypass, venous ...

  • Possible Roxithromycin-Induced Fulminant Hepatic Failure ...
    ... copper and 1-antitrypsin levels were ... was transferred to intensive care and began receiving neomycin and lactulose. ... Alpha-1-antitrypsin deficiency. ...

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December 2, 2009



Page Updated: January 17, 2009
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