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Amantadine as related to Apert syndrome


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Symadine; Symmetrel 

Acrocephalosyndactyly (Apert); Acrocephaly 

Amantadine, 1-adamantane amine, is an antiviral drug that was approved by the FDA in 1976 for the treatment of influenza type A in adults. The drug has also been demonstrated to help reduce symptoms of Parkinson's disease and drug-induced short-term extrapyramidal syndroms. As an antiparkinsonic it is being prescribed together with L-DOPA when L-DOPA responses decline (probably due to tolerance).

Apert syndrome is a genetic disorder characterized by the premature fusion of certain bones of the skull (craniosynostosis), which prevents further growth of the skull and affects the shape of the head and face. In addition, a varied number of fingers and toes are fused together (syndactyly). Many of the characteristic facial features of Apert syndrome result from the premature fusion of the skull bones. The head is unable to grow normally, which leads to a sunken appearance in the middle of t...


Amantadine as related to Apert syndrome


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December 2, 2009


Page Updated: January 17, 2009
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