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Amantadine as related to Chagas Disease


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Symadine; Symmetrel 

American Trypanosomiasis; South American Trypanosomiasis 

Amantadine, 1-adamantane amine, is an antiviral drug that was approved by the FDA in 1976 for the treatment of influenza type A in adults. The drug has also been demonstrated to help reduce symptoms of Parkinson's disease and drug-induced short-term extrapyramidal syndroms. As an antiparkinsonic it is being prescribed together with L-DOPA when L-DOPA responses decline (probably due to tolerance).

Chagas disease (also called American trypanosomiasis) is a Mammalian disease occurring only in the Americas. It is caused by the protozoan Trypanosoma cruzi, one of the kinetoplastid flagellates, transmitted to humans by triatomine insects known in the different countries as assassin bug, vinchuca, kissing bug, chipo, barbeiro, etc. Common triatomine vector species for trypanosomiasis belong to the genera Triatoma, Rhodinius, and Panstrongylus.


Amantadine as related to Chagas Disease


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November 27, 2009


Page Updated: January 17, 2009
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