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Metformin as related to Alport syndrome


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congenital hereditary hematuria; hemorrhagic familial nephritis; hemorrhagic hereditary nephritis; Hereditary nephritis 

Metformin (Glucophage®) is an anti-diabetic drug from the biguanide class (its other members are the withdrawn agents phenformin and buformin).

Alport syndrome is a genetic condition characterized by the progressive loss of kidney function and hearing. Alport syndrome can also affect the eyes. The presence of blood in the urine (hematuria) is almost always found in this condition. Many people with Alport syndrome also exhibit high levels of protein in their urine (proteinuria). As this condition progresses, the kidneys become less able to function properly and kidney failure results. Hearing loss is a common feature of Alport syndro...


Metformin as related to Alport syndrome


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November 24, 2009


Page Updated: January 17, 2009
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