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Aldactone |
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Spironolactone (marketed as Aldactone or Spiritone) is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat low-renin hypertension, hypokalemia, and Conn's syndrome. On its own, spironolactone is only a weak diuretic, but it can be combined with other diuretics. ...
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Central pontine myelinolysis is a neurologic disease caused by severe damage of the myelin sheath of nerve cells in the brainstem, more precisely ...
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Spironolactone as related to Central pontine myelinolysis
- ISPUB - Management of hyponatraemia in cirrhotic ascites
... can be followed by cessation of spironolactone if sodium levels do not respond ... by more than 12meq/l per day is necessary to avoid central pontine myelinolysis. ...
- Part 8: Advanced Challenges in Resuscitation : Section 1 ...
... sparing diuretics such as spironolactone, triamterene, and amiloride are well ... Central pontine myelinolysis and pontine lesions after rapid correction of ...
- management - General Practice Notebook
... distal-acting diuretic such as spironolactone along with a loop diuretic ... Excessively rapid correction of hyponatraemia may cause central pontine myelinolysis. ...
- CME LLC
... central pontine myelinolysis, which can lead to irreversible degeneration of nerve fibers. ... Spironolactone is making a tremendous rebirth, Mende said, ...
- Secrets Series Usmle Step 2
USMLE SECRETS Step 2 and 3 Ayala usmle secrets step ... pontine myelinolysis) ... but proven to work), diuretics, spironolactone, digoxin (not used in diastolic ...
- Section 10 Chapter I Renal Function and Disorders of Water ...
Complications of Therapy: Myelinolysis and Osmotic Demyelination Syndrome ... the center of the basal pons (central pontine myelinolysis), but histologically ...
- Lasix (Furosemide) - Mahalo
Spironolactone (Aldactone) Eplerenone (Inspra) Lasix (Furosemide) Clinical Studies and Research ... PubMed: Diuretic Abuse and Central Pontine Myelinolysis ...
- JAMA -- Table of Contents (Vol. 184 No. 13, June 29, 1963)
Cytoplasmic Bodies in the Adrenal Cortex of Patients Treated with Spironolactone ... Central Pontine Myelinolysis. JAMA. 1963;184(13):173. FULL TEXT PDF ...
- All Articles - Medpedia
Aldactazide (spironolactone and hydrochlorothiazide) (Clinical) ... Central Cord Syndrome. Central Core Disease. Central Pain Syndrome. Central Pontine Myelinolysis ...
- World J Gastroenterol
... as furosemide and spironolactone with careful monitoring of creatinine and ... in malnourished patients, could lead to fatal central pontine myelinolysis. ...
- Secrets Series - Usmle Step 2
We respect your privacy and won't send any ... pontine myelinolysis) ... but proven to work), diuretics, spironolactone, digoxin (not used in diastolic ...
- Endocrinology (Dec.1999)
... in the development of central pontine myelinolysis, a serious complication. ... Treatment is surgical for adenoma or medical for hyperplasia with spironolactone. ...
- Arginine Vasopressin Antagonists for the Treatment of Heart ...
... feared complications of central pontine myelinolysis from too-rapid correction of serum sodium. ... placebo, in addition to spironolactone 100 mg daily for ...
- the Drug Monitor - Post-Operative Nursing Care for the Liver ...
Diuretic therapy: Spironolactone and Furosemide (either drug alone is generally ... Tx: To be corrected slowly (central pontine myelinolysis) with fluid restriction. ...
- Microsoft PowerPoint - K.lee1030am [Compatibility Mode]
... in baseline for complete central DI, and ... (Central Pontine Myelinolysis and encephalopathy) For low extracellular vol ... Spironolactone (150mg-300mg PO/D) ...
- Preoperative Assessment of the Patient with Liver Disease
central pontine myelinolysis (78). A patient with ESLD and renal insufficiency may require ... Sodium restriction and diuretics such as spironolactone and ...
- Management of pre-liver transplantation patient-Part 2
complications, such as central pontine myelinolysis, ... ride can be substituted for spironolactone, but it is more ... on central pontine mye- linolysis. ...
- Refractory Ascites: Pathogenesis, Clinical Impact, and Management
response to maximal doses of diuretic (spironolactone ... fear of precipitating central pontine myelinolysis. Hepatorenal Syndrome ...
- 2006 –2007
Caution: central pontine myelinolysis if hyponatremia corrected too quickly. ... Aldosterone antagonist Spironolactone (Aldactone, Gens) 25-100mg q8h. 2.5.3 ...
- RESIDENT SURVIVAL GUIDE 2004-2005 Introduction
Correction too fast may result in central pontine myelinolysis (flaccid paralysis, dysarthria, ... state, drugs (spironolactone, ACE inhibitor, digitalis ...

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