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Spironolactone as related to Chagas Disease


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Aldactone 

American Trypanosomiasis; South American Trypanosomiasis 

Spironolactone (marketed as Aldactone or Spiritone) is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat low-renin hypertension, hypokalemia, and Conn's syndrome. On its own, spironolactone is only a weak diuretic, but it can be combined with other diuretics. ...

Chagas disease (also called American trypanosomiasis) is a Mammalian disease occurring only in the Americas. It is caused by the protozoan Trypanosoma cruzi, one of the kinetoplastid flagellates, transmitted to humans by triatomine insects known in the different countries as assassin bug, vinchuca, kissing bug, chipo, barbeiro, etc. Common triatomine vector species for trypanosomiasis belong to the genera Triatoma, Rhodinius, and Panstrongylus.


Spironolactone as related to Chagas Disease


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November 23, 2009


Page Updated: January 17, 2009
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