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Acidosis as related to Metformin


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Acidosis is any condition tending to elevate the hydrogen ion concentration of arterial plasma, making the blood more acidic. Generally, acidosis is said to occur when pH falls below 7.35. Its counterpart (alkalosis) occurs at a pH over 7.45. Arterial blood gas analysis and other tests are required to seperate the main causes.

Metformin (Glucophage®) is an anti-diabetic drug from the biguanide class (its other members are the withdrawn agents phenformin and buformin).


Acidosis as related to Metformin


  • Metformin Information from Drugs.com
    Metformin information from Drugs.com, includes Metformin side ... An overdose of metformin may cause a life-threatening condition called lactic acidosis. ...

  • Metformin and Fatal Lactic Acidosis
    Metformin useful but small risk of potentially fatal lactic acidosis ... Examples of metformin-induced lactic acidosis cases reported to CARM include: ...

  • Metformin and Lactic Acidosis
    This eMedTV resource looks at a life-threatening potential side effect of metformin: lactic acidosis. This page describes some of the symptoms of lactic acidosis and ...

  • Metformin - Wikipedia, the free encyclopedia
    ... with Regard to Metformin-Induced Lactic Acidosis and X-ray Contrast ... Severe lactic acidosis complicating metformin overdose successfully treated with ...

  • Metformin
    Lactic acidosis is a rare, but potentially severe consequence of therapy with metformin. ... agents: May increase the risk of metformin-induced lactic acidosis. ...

  • [Metformin-associated lactic acidosis]
    The keywords were: lactic acidosis, metformin, biguanide, diabetes mellitus. ... The incidence of metformin-associated lactic acidosis is very low when contra ...

  • How to Metformin Description | eHow.com
    How to article - metformin description. Metformin, also known as Glucophage, is used in conjunction with the treatment of type-2 diabetes. Prescribed in a tablet...

  • Metformin
    Lactic acidosis is caused by metformin accumulation in patients with kidney ... Metformin No Increase in Lactic Acidosis: A meta-analysis covering 56,000 ...

  • Lactic acidosis in metformin therapy: searching for a link ...
    ... analysing published reports of so-called 'metformin-associated lactic acidosis' ... patients with lactic acidosis where plasma metformin concentration data was not ...

  • Metformin - Yahoo! Health
    Before taking metformin, tell your doctor if you have liver disease ... An overdose of metformin may cause a life-threatening condition called lactic acidosis. ...

  • Metformin, Glucophage and Glucovance
    Metformin, Glucophage and Glucovance, are type 2 medications which lower the livers glucose production as well as increasing ... lactic acidosis when other ...

  • Health Links Content: Lactic acidosis: Lactic acidosis ...
    Lactic acidosis associated with metformin use in the treatment of type 2 diabetes mellitus. ... Metformin was discontinued when it was determined that the ...

  • Metformin (Oral route)
    When metformin is implicated as the cause of lactic acidosis, metformin plasma ... to metformin in clinical trials, there were no reports of lactic acidosis. ...

  • Glumetza
    When metformin is implicated as the cause of lactic acidosis, metformin plasma ... is recommended to correct the acidosis and remove the accumulated metformin. ...

  • Metformin-Induced Lactic Acidosis Is Found to Be Rare - April ...
    No cases of lactic acidosis were seen in the metformin-treated group or in the comparison group. ... Metformin-induced lactic acidosis extremely rare. ...

  • Glyburide and metformin (Oral route)
    When metformin is implicated as the cause of lactic acidosis, metformin plasma ... metformin hydrochloride do not necessarily indicate impending lactic acidosis ...

  • Diabetes Monitor: Metformin Questions and Answers
    Features patient information for the Type 2 diabetes medication sold under the ... Lactic acidosis caused by GLUCOPHAGE (metformin hydrochloride tablets) and ...

  • RIOMET® - Ranbaxy Laboratories, Inc. - Home: Have you heard ...
    Riometâ„¢ (metformin HCl oral solution) is the first and only liquid metformin to ... When metformin is implicated as the cause of lactic acidosis, metformin plasma ...

  • Glucovance (Glyburide / Metformin) - Warnings and Precautions
    When metformin is implicated as the cause of lactic acidosis, metformin plasma ... is recommended to correct the acidosis and remove the accumulated metformin. ...

  • Critical Care | Full text | Metformin-associated lactic ...
    Metformin-associated lactic acidosis in an intensive care unit ... Metformin-associated lactic acidosis (MALA) is a classic side effect of ...

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December 5, 2009



Page Updated: January 17, 2009
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