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Marfan Syndrome as related to Canavan Disease


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Arachnodactyly; MFS 

ACY2 deficiency; Aminoacylase 2 deficiency; Asp deficiency; Aspa deficiency; Aspartoacylase deficiency; Leukodystrophy, ... 

Marfan syndrome is a heritable condition that affects the connective tissue. The primary purpose of connective tissue is to hold the body together and provide a framework for growth and development. In Marfan syndrome, the connective tissue is defective and does not act as it should. Because connective tissue is found throughout the body, Marfan syndrome can affect many body systems, including the skeleton, eyes, heart and blood vessels, nervous system, skin, and lungs.

Canavan disease is an inherited disorder of the central nervous system in which affected individuals cannot break down a compound called N-acetyl-L-aspartic acid (NAA). Canavan disease is one of a group of genetic disorders called the leukodystrophies. The signs and symptoms of this disease usually begin early in infancy. The course of the condition can be quite variable, however. Signs and symptoms include developmental delay, particularly in motor skills such as such as sitting, standing, an...


Marfan Syndrome as related to Canavan Disease


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November 23, 2009


Page Updated: January 17, 2009
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