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GERD as related to Esomeprazole


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Acid Reflux; Gastroesophageal Reflux; Gastroesophageal Reflux (GERD); Gastroesophageal Reflux Disease; Gastroesophageal ... 

Nexium 

Gastroesophageal reflux disease, or GERD, occurs when the lower esophageal sphincter (LES) does not close properly and stomach contents leak back, or reflux, into the esophagus. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach. The esophagus carries food from the mouth to the stomach.

Esomeprazole is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease (PUD), GERD and Zollinger-Ellison syndrome. Esomeprazole magnesium trihydrate is marketed by AstraZeneca under the tradename Nexium®. Esomeprazole is the S-enantiomer of omeprazole (marketed as Losec® & Prilosec®), and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic mixture of omeprazole (see below). ...


GERD as related to Esomeprazole


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November 7, 2009


Page Updated: January 17, 2009
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