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Alpha-1 Antitrypsin Deficiency as related to Dexamethasone


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AAT; alpha-1 proteinase inhibitor; alpha-1 related emphysema; genetic emphysema; hereditary pulmonary emphysema; inherit... 

 

Alpha-1 is an inherited disorder that may result in you developing a serious lung/ liver disease and passing the defective AAT gene onto your children. An estimated 100,000 people in the U.S. and a similar number in Europe are estimated to have the severe deficiency. In normal individuals large amounts of alpha-1 antitrypsin (AAT) is made in the liver and released into the blood. In AAT deficient individuals, the AAT made in the liver cannot be fully released into the blood.

A synthetic steroid (similar to steroid hormones produced naturally in the adrenal gland). Dexamethasone is used to treat leukemia and lymphoma and may be used to treat some of the problems caused by other cancers and their treatment.


Alpha-1 Antitrypsin Deficiency as related to Dexamethasone


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November 23, 2009


Page Updated: January 17, 2009
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