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Alpha-1 Antitrypsin Deficiency as related to Cirrhosis


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AAT; alpha-1 proteinase inhibitor; alpha-1 related emphysema; genetic emphysema; hereditary pulmonary emphysema; inherit... 

Cirrhosis (Primary Biliary); Cirrhosis of the Liver; Liver Cirrhosis 

Alpha-1 is an inherited disorder that may result in you developing a serious lung/ liver disease and passing the defective AAT gene onto your children. An estimated 100,000 people in the U.S. and a similar number in Europe are estimated to have the severe deficiency. In normal individuals large amounts of alpha-1 antitrypsin (AAT) is made in the liver and released into the blood. In AAT deficient individuals, the AAT made in the liver cannot be fully released into the blood.

A type of chronic, progressive liver disease in which liver cells are replaced by scar tissue.


Alpha-1 Antitrypsin Deficiency as related to Cirrhosis


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November 23, 2009


Page Updated: January 17, 2009
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