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Alpha-1 Antitrypsin Deficiency as related to Chronic Obstructive Pulmonary Disease


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AAT; alpha-1 proteinase inhibitor; alpha-1 related emphysema; genetic emphysema; hereditary pulmonary emphysema; inherit... 

Chronic Obstructive Pulmonary Disease (COPD) 

Alpha-1 is an inherited disorder that may result in you developing a serious lung/ liver disease and passing the defective AAT gene onto your children. An estimated 100,000 people in the U.S. and a similar number in Europe are estimated to have the severe deficiency. In normal individuals large amounts of alpha-1 antitrypsin (AAT) is made in the liver and released into the blood. In AAT deficient individuals, the AAT made in the liver cannot be fully released into the blood.

Chronic obstructive pulmonary disease (COPD) is an umbrella term for a group of respiratory tract diseases that are characterised by airflow obstruction or limitation. It is usually caused by smoking.


Alpha-1 Antitrypsin Deficiency as related to Chronic Obstructive Pulmonary Disease


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November 23, 2009


Page Updated: January 17, 2009
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