Smallpox (also known by the Latin names Variola or Variola vera) is a highly contagious disease unique to humans. It is caused by two virus variants called Variola major and Variola minor. V. major is the more deadly form, with a typical mortality of 20-40 percent of those infected. The other type, V. minor, only kills 1% of its victims. Many survivors are left blind in one or both eyes from corneal ulcerations, and persistent skin scarring - pockmarks - is nearly universal. ...

Anthrax is an acute disease caused by Bacillus anthracis. It affects both humans and animals and most forms of the disease are highly lethal. There are effective vaccines against anthrax, and some forms of the disease respond well to antibiotic treatment.

Smallpox as related to Cutaneous anthrax