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Fibromyalgia as related to Melatonin


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MEL; MLT; N-acetyl-5-methoxytryptamine 

Fibromyalgia syndrome is a common and chronic disorder characterized by widespread muscle pain, fatigue, and multiple tender points. The word fibromyalgia comes from the Latin term for fibrous tissue (fibro) and the Greek ones for muscle (myo) and pain (algia). Tender points are specific places on the body; on the neck, shoulders, back, hips, and upper and lower extremities; where people with fibromyalgia feel pain in response to slight pressure.

Melatonin, or 5-methoxy-N-acetyltryptamine, is a hormone produced by pinealocytes in the pineal gland, located in the brain, but also in the retina and GI tract. It is a derivative of the amino acid tryptophan.


Fibromyalgia as related to Melatonin


  • The effect of melatonin in patients with fibromyalgia: a pilot study.
    ... sleep, fatigue and pain symptoms observed in fibromyalgia (FM) patients. ... Before and after treatment with melatonin 3 mg at bedtime, patients were ...

  • Herbs and Supplements That May Help Fibromyalgia
    ... and supplements to treat your fibromyalgia symptoms? Here's information from WebMD ... Can melatonin help relieve sleep problems associated with fibromyalgia? ...

  • NutriNewsSpring-2005
    page 6. Melatonin Replacement Therapy . . . . . . page 7. Malabsorption in Fibromyalgia: ... of melatonin by 200%. 46, 47. 5HTP and Fibromyalgia ...

  • Fibromyalgia
    People with fibromyalgia have decreased activity in opioid receptors in parts of ... Melatonin is important in regulating the sleep-wake cycle. ...

  • Dominie's 100 Tips for Coping with Fibromyalgia (FMS), Insomnia and ...
    Dominie's Tips #1-10 for coping with fibromyalgia, insomnia and chronic fatigue syndrome. ... Melatonin worked well for me for 5 years, until I reached menopause. ...

  • How to Use Melatonin Correctly
    Sleep disorder community providing authoritative sleep information and live sleep disorder support: news, ... National Fibromyalgia Association. PAPillow. Our ...

  • National Fibromyalgia Association: Melatonin: Helpful or Harmful?
    The National Fibromyalgia Association's mission is to develop and execute programs dedicated to improving the quality of life for people with fibromyalgia.

  • Fibromyalgia
    Fibromyalgia is relatively common disorder affecting primarily women in the 25 ... Melatonin. Magnesium. Vitamin D. Menthol. Cayenne. Massage for sleep (20 min. ...

  • National Fibromyalgia Association: Fibromyalgia and Medication
    Multiple articles on fibromyalgia and medication ... Melatonin: Helpful or Harmful? Melatonin has become a popular therapy, used to promote sleep or fight jetlag. ...

  • Fibromyalgia
    Melatonin. Vitamin B1 (thiamine) Vitamin B12 (cobalamin) Vitamin B2 (Riboflavin) ... More women than men have fibromyalgia. ... Melatonin (0.5 - 3 mg one time ...

  • MotherNature.com - Melatonin
    Melatonin is a natural hormone that regulates the human biological clock. ... Melatonin may be useful in the treatment of fibromyalgia. ...

  • Fibromyalgia
    A study that purportedly found melatonin helpful was, in fact, too poorly ... JA, et al. The effect of melatonin in patients with fibromyalgia: a pilot study. ...

  • Manga Report, Dr Larry Smith, Chiropractor
    ... Fibromyalgia-a syndrome associated with decreased nocturnal ... 15. Citera G, et al. The effect of melatonin in patients with fibromyalgia: a pilot study. ...

  • Fibromyalgia - Abstracts : Online Reference for Health Concerns
    Does exogenous melatonin influence the free radicals metabolism and pain sensation in rat? ... [ Melatonin influences the release of endogenous opioid peptides ...

  • Arthritis Today Magazine l Supplement Guide l Alternative Therapies
    ... and sleep disturbances related to conditions like fibro­my­algia and depression. ... Another review of studies showed that melatonin reduced the onset of sleep by ...

  • New Zealand Fibromyalgia Information
    ... to support people in Pacific countries with Fibromyalgia (FM or Fibro) Pain Chronic Fatigue Syndrome (CFS) ... pain of fibromyalgia. Melatonin. Melatonin ...

  • Melatonin: Helpful or Harmful?
    Sleep disorder community providing authoritative sleep information and live sleep disorder ... Some Fibromyalgia treatments may further lower melatonin levels. ...

  • ~Fibromyalgia
    Fibromyalgia is a condition characterized by severe muscle pain. ... Melatonin also crosses the blood-brain barrier very effectively. ...

  • PCC | Healthnotes | Melatonin
    Melatonin is a natural hormone that regulates the human biological clock. ... no current rationale for melatonin supplementation in people with fibromyalgia. ...

  • Fibromyalgia - Page 2 Of 2: Online References For Health Concerns
    Fibromyalgia ... Studies have found that people with fibromyalgia have low melatonin levels. ... patients with fibromyalgia produce less melatonin during hours ...

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November 9, 2009


Page Updated: January 17, 2009
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