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Cirrhosis as related to Alpha-1 Antitrypsin Deficiency


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Cirrhosis (Primary Biliary); Cirrhosis of the Liver; Liver Cirrhosis 

AAT; alpha-1 proteinase inhibitor; alpha-1 related emphysema; genetic emphysema; hereditary pulmonary emphysema; inherit... 

A type of chronic, progressive liver disease in which liver cells are replaced by scar tissue.

Alpha-1 is an inherited disorder that may result in you developing a serious lung/ liver disease and passing the defective AAT gene onto your children. An estimated 100,000 people in the U.S. and a similar number in Europe are estimated to have the severe deficiency. In normal individuals large amounts of alpha-1 antitrypsin (AAT) is made in the liver and released into the blood. In AAT deficient individuals, the AAT made in the liver cannot be fully released into the blood.


Cirrhosis as related to Alpha-1 Antitrypsin Deficiency


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November 23, 2009


Page Updated: January 17, 2009
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