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Spondylitis, Ankylosing 

Azulfidine; Azulfidine EN-tabs; Sulfazine EC 

Ankylosing Spondylitis (AS) is the main rheumatic disease in a group of conditions called the spondyloarthropathies (SpA). Collectively, they are referred to as spondylitis. Although AS primarily affects the mobility of the spine, it rarely affects the entire spine. Sometimes other areas of the body such as the eyes and or small joints of the hands and feet can be involved, but there are treatments available to reduce symptoms.

Sulfasalazine is a sulfa drug used primarily in the treatment of inflammatory bowel disease. It is a 5-acetylsalicyclic acid derivative. It is sold as Azulfidine in the United States. It is also used for rheumatoid arthritis. It is usually not given to children under 2 years of age.


Ankylosing Spondylitis as related to Sulfasalazine