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Amyotrophic Lateral Sclerosis as related to Riluzole


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Als; Amyotrophic Lateral Sclerosis (ALS); Amyotrophic lateral sclerosis, type 2; Amyotrophic lateral sclerosis, type 4; ... 

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Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a progressive, fatal neurological disease affecting as many as 20,000 Americans with 5,000 new cases occurring in the United States each year. The disorder belongs to a class of disorders known as motor neuron diseases. ALS occurs when specific nerve cells in the brain and spinal cord that control voluntary movement gradually degenerate. The loss of these motor neurons causes the muscles under their control to weaken and w...

Riluzole is a drug used to treat amyotrophic lateral sclerosis. It delays the onset of ventilator-dependence in selected patients and may increase survival by approximately two months. A Cochrane Library review states a 9% gain in the probability of surviving one year. In secondary analyses of survival at separate time points, there was a significant survival advantage with Riluzole 100 mg at six, nine, 12 and 15 months, but not at three or 18 months. ...


Amyotrophic Lateral Sclerosis as related to Riluzole


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November 22, 2009


Page Updated: January 17, 2009
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