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Alzheimer's Disease as related to Selective Serotonin Reuptake Inhibitors (SSRIs)


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AD; Alzheimer disease; Alzheimer//'s disease; Alzheimer///'s disease; DAT - Dementia Alzheimer's type; familial Alzheime... 

 

Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized in the brain by abnormal clumps (amyloid plaques) and tangled bundles of fibers (neurofibrillary tangles) composed of misplaced proteins. Age is the most important risk factor for AD; the number of people with the disease doubles every 5 years beyond age 65. Three genes have been discovered that cause early onset (familial) AD. Other genetic mutations that cause excessive accumulation of amyloid protein are associ...

Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants. They act within the brain to increase the amount of the neurotransmitter, serotonin (5-hydroxytryptamine or 5-HT), in the synaptic gap by inhibiting its reuptake. One notable characteristic of SSRIs is that, unlike other classes of antidepressants, SSRIs were rationally designed drugs. Instead of being discovered by accident, SSRIs were specifically designed while considering the biological causes of depression. ...


Alzheimer's Disease as related to Selective Serotonin Reuptake Inhibitors (SSRIs)


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November 23, 2009


Page Updated: January 17, 2009
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