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Tranylcypromine as related to Anxiety - Pictures
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(e.g. Acne, Diabetes, Acupuncture, Homeopathy, etc.)
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Parnate
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Anxiety Disorders
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Pictures
0506cnsPatkar5 jpg
tranylcypromine 49 50 Even with long term STS 6 mg 24 hours treatment there is only a slight increase in tyramine sensitivity compared with that seen with oral selegiline 10 mg day 51 The results of tyramine challenge studies48 50 suggest that STS 6 mg 24 hours is equivalent to oral selegiline 10 mg day in pressor responses at 10 days and is ~20 times less sensitive
0507CNS RTM Slide11 jpg
to metabolize tyramine and dopamine MAO A also has a high affinity for norepinephrine and serotonin whereas MAO B has a high affinity for phenylethanolamine and benzylamine Slide 11 14 The older MAOIs like phenelzine and tranylcypromine were effective antidepressants but could cause serious adverse effects when patients treated with them consumed food rich in tyramine
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