GERD		Pantoprazole
Acid Reflux; Gastroesophageal Reflux; Gastroesophageal Reflux (GERD); Gastroesophageal Reflux Disease; Gastroesophageal ...		Protonix

Pictures

Pantoprazole jpg

---

generic protonix pantoprazole sodium clip image005 jpg

and persistent nighttime heartburn can be a symptom of erosive Gastroesophageal reflux disease or erosive GERD in which sores develop in the lining of the esophagus 8 ADVERSE SIDE EFFECTS of PROTONIX

---

generic protonix pantoprazole sodium clip image003 jpg

bulges into the chest cavity through an opening in the diaphragm hiatus The diaphragm is a sheet of muscle that separates the stomach cavity from the chest cavity What are the symptoms of GERD Heartburn is the most common symptom of GERD It feels like a burning chest pain right behind the breastbone Pain

---

generic protonix pantoprazole sodium clip image001 jpg

the stomach Reflux means to back up or flow backwards GERD is a condition in which acid bile and partially digested food in the stomach back up into the esophagus

---

tab138 jpg

CONCLUSION In patients with moderate to severe GERD treatment with pantoprazole 40 mg and esomeprazole 40 mg led to low symptom load values within 4 weeks of treatment

---

images2 jpeg

PROTONIX has become the number one oral proton pump inhibitor PPI in hospitals Here are some of the reasons PROTONIX is used to treat erosive GERD gastroesophageal reflux disease a

---

n2 r1 c2 jpg

---

images26 jpeg

PROTONIX helps to control NIGHTTIME heartburn and other symptoms associated with erosive GERD daytime heartburn acid reflux and difficulty swallowing Most patients who have erosive GERD

---

PROTONIX gif

---

protonix 220 jpg

Protonix Pantoprazole Description autotranslated Common uses This medicine is a proton pump inhibitor PPI used to treat ulcers gastroesophageal reflux disease GERD erosive esophagitis or Zollinger Ellison syndrome This

---

pantalocadd001 gif

---

feldmans jpg

Images

---

hp img main jpg

---

congresses jpg

Congresses

---

exir pharmaceutical 03 jpg

---

exir pharmaceutical 01 jpg

---

slide06 gif

more difficult Rabeprazole and lansoprazole have a more rapid onset of relief than omeprazole and pantoprazole in the first few days of therapy Esomeprazole is more rapid than omeprazole Slide 6 Satisfactory Heartburn Relief With Rabeprazole 20 mg Daily We can look at the Fass trial in which patients had EE and you can see this dramatic relief of symptoms in the first day

---

slide10 gif

are quite different Omeprazole and pantoprazole are mostly metabolized by 2C19 lansoprazole is metabolized by 2C19 and 3A4 while rabeprazole is mostly metabolized by nonenzymatic pathways Slide 6 Genetic Polymorphism of CYP2C19 It is relevant because we know now that there is an important genetic polymorphism of CYP2C19 We can differentiate between rapid metabolizers with a

---

slide12 gif

Omeprazole pantoprazole and lansoprazole have high values while rabeprazole has a value near 1 Therefore it is not affected by the difference between extensive and poor metabolizers Slide 8 PPIs CYP2C19 Genotype and Gastric pH What is the consequence of that on gastric pH It is immediately evident that in contrast to lansoprazole which shows major differences between

---

slide18 gif

in a distant second by lansoprazole gave you a much better inhibition of gastric acid secretion on day 1 than did either pantoprazole or omeprazole or the omeprazole in the pellet suspension Slide Rabeprazole vs Omeprazole Rapidity of Symptom Relief We re starting to see some literature now that these agents that do have better day 1 efficacy and in particular rabeprazole does

---