Meningitis - H. influenzae

Pictures

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to H influenzae type b infection In addition opsonizing antibodies which also play a role in protection may be directed against PRP as well as somatic constituents Figure 5 Figure 5 Phagocytic engulfment of H influenzae bacterium opsonized by antibodies specific for the capsule and somatic cell wall antigens Recent studies of nontypable H influenzae

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Haemophilus influenzae meningitis Overall incidence

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H influenzae meningitis hospitalisation rate Figure 2 H influenzae type b Hib notification and presumed Hib hospitalisation rates Australia 2000 to 2002 by age at admission Notifications where the month of onset was between January 2001 and December 2002 hospitalisations where the month of separation was between 1 July 2000 and 30 June 2002

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during the winter months Figure 1 H influenzae type b Hib notifications and presumed Hib hospitalisations for all ages Australia 1993 to 2002 by month of onset or admission Hospitalisations for H influenzae meningitis and acute epiglottitis

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Figure 3 H influenzae type b Hib notification and presumed Hib hospitalisation rates and numbers of deaths for children aged 0 4 years Australia 1993 to 2002 Hospitalisations for H influenzae meningitis and acute epiglottitis

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cases of meningitis caused by H influenzae from 25 8 in the pre vaccine period to 15 9 in the post vaccine period p<0 05 especially in the seven to 23 months age group p<0 01 Figure 1 On the other hand there was a significant increase in S pneumoniae cases from 2 7 to 12 8

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among the pathogenic agents of bacterial meningitis during July 1997 through June 2000 H influenzae was most prevalent followed by S pneumoniae GBS and E coli in this order Table 1 Among the age distribution of the patients yielding the most prevalent bacterial species Fig 4 those yielding GBS were mainly infants under 4 months of age and those yielding

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notable bacterial species were Staphylococcus aureus 17 Staphylococcus epidermidis 15 Coagulase negative Staphylococcus CNS 10 H influenzae 11 and S pneumoniae 7 Fig 3 Surveys for pediatric bacterial meningitis cases in Japan According to the three surveys conducted by H Kamiya and his associates during 1994 1998 60 70 of the etiological

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is obvious that artificial active immunization should begin at 2 months of age when nearly all passive immunity has waned and the child enters a vulnerable non immune period of life Figure 4 Relation of the age incidence of bacterial meningitis caused by Haemophilus influenzae to bactericidal antibody titers in the blood data pre 1985 H influenzae is

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and 8 in 2001 Their ages ranged from 0 to 71 years 6 cases each were 0 year 1 14 years and 15 19 years and 15 cases of adults Male cases numbered 28 and female ones numbered 5 Fig 2 Infectious agent surveillance Of all 96 etiological agents that were isolated from meningitis patients during 1995 2001 28 each were H influenzae and S pneumoniae according

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was most prevalent followed by S pneumoniae GBS and E coli in this order Table 1 Among the age distribution of the patients yielding the most prevalent bacterial species Fig 4 those yielding GBS were mainly infants under 4 months of age and those yielding E coli were all infants under 2 months of age Those yielding H influenzae were principally at

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H influenzae meningitis

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H ducreyi H influenzae Berbentuk pleomorfik menyebabkan meningitis bakteria akut pada kanak kanak dan bayi dan penyakit pulmonari kronik pada orang dewasa Mula mula dipencilkan oleh Pfeiffer pada 1890 semasa

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is smaller in size than E coli For a relatively obscure bacterium there was already a good understanding of its genetic processes especially transformation Figure 2 A map of the circular chromosome of Haemophilus influenzae illustrating the location of known genes and predicted coding regions Observations of genetic

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from very short to very long rods Figure 5 H influenzae typically infects children under five years of age causing otitis media respiratory infections and meningitis Figure 5 Gram stain of Haemophilus influenzae Arrows show very short gram negative rods and also long rods in the same specimen Another group of gram negative rods

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The mean number of Meningococcal disease cases per quarter per age group is 2 0 + 0 1 N= 165 = 33 quarters 5 age groups variance= 3 4 with minimum 0 and maximum 11 Figure 3 shows that the number of Meningococcal and H influenzae meningitis change very similarly over time except for the period 1998 2000 before starting H influenzae

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Nontypable H influenzae causes ear infections otitis media and sinusitis in children and is associated with respiratory tract infections pneumonia in infants children and adults Figure 3 Tissues infected by type b and nontypable strains of Haemophilus influenzae Seven serotypes of the bacterium have been identified on the basis of capsular polysaccharides Until

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Or your parents would not have taken you to an H influenza party to get HIB meningitis and spend the rest of your life like this provided you survived http www kianh org uk tuan5 JPG Haemophilus influenzae type b can cause serious diseases especially in children under 5 years of age It was the leading cause of bacterial meningitis before

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E coli comenzaron después de las 72 h de vida y en 46 pacientes 69 7 se constató hemocultivo positivo coincidente siendo la concordancia del 84 para EGB y del 67 para E coli De las 8 meningitis probables se aisló EGB en el hemocultivo en 5 casos 62 5 y E coli Haemophilus influenzae y L monocytogenes en uno Un caso de meningitis probable a EGB y

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Imágenes Haemophilus influenzae

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