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state The cross hatched area represents the expected overlap in plasma concentrations due to intersubject variation following oral administration of 1 000 mg to 2 000 mg of Nabumetone Nabumetone Active Metabolite 6MNA Plasma Concentrations at Steady State Following Once Daily Dosing of Nabumetone 1 000 mg n = 31 2 000 mg n = 12 6MNA undergoes biotransformation in the

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