Not Signed In - HMGA1 Stops P53 In Its Tracks In Cancer Cells
Wed, 14 Feb 2007 01:00 PM EST
... Overexpression of a protein known as HMGA1 has been associated with many types of cancer in humans. Previous studies have shown that HMGA1 decreases the ability of p53 to inhibit cell death by a process known as apoptosis; inhibition of p53-mediated apoptosis causes tumors to develop in both animals and humans. [click link for full article] ...
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