Mind Over Matter: SH2B1 In The Brain Regulates Obesity

... Obesity is one of the main risk factors for developing type II diabetes. Previous studies have shown that mice lacking a protein known as SH2B1 throughout their body are obese and develop diabetes. However, researchers from the University of Michigan have now shown that replacing SH2B1 only in the brain of these mice rescues them from obesity, indicating that targeting SH2B1 in the brain might be a new avenue of research for the development of treatments for obesity and type II diabetes. ...