HFI-1 Gene Has Key Role In Both Oxygen Sensing, Heat Shock Pathway

... University of Oregon researchers have found an unexpected regulatory link between cellular responses to hypoxia and heat shock. Central to the discovery is a gene known as Hypoxia-Inducible Factor-1 (HIF-1) that is critical for both normal and pathological changes, making it a potential target for both health promotion and cancer therapies. [click link for full article] ...