Separating Muscle Damage From Neurodegeneration In Kennedy Disease

... Kennedy disease is a neurodegenerative disorder caused by mutations in the gene encoding the receptor for testosterone, the androgen receptor (AR). Although it is characterized by muscle weakness caused by neurodegeneration, individuals with Kennedy disease often first suffer from muscle cramps. How the diseases progresses from muscle cramps to neuromuscular weakness is not clear. [click link for full article] ...