Probing Repetitive Firing In Pyramidal Neurons

... In response to a continuous stimulus, some neurons slow their firing rate, an adaptation process that is mediated by slow, voltage-dependent potassium channels such as IM and IAHP. This week, Prescott et al. show that adaptation can be modulated by membrane conductance, or shunting, as occurs with background synaptic activity. [click link for full article] ...