Recent Blog Posts

View Post: Mama Monkmee: Key Chains For Sale
27 Aug 2008 by Dawn  
Silver Ribbon: Brain Disabilities, Brain Disorders, Campaign for the Brain, Disabled Children, Dyslexia, Elderly Abuse, Encephalitis, Niemann-Pick, Parkinson's Disease, Schizophrenia, Sciatic Pain, VACTERL & Young Onset Parkinson's ...
View Blog: Mama Monkmee - http://mamamonkmee.blogspot.com/

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View Post: FDA Approves First Ever Cyclodextrin Infusion Treatment For Twin ...
15 Mar 2009 by Chris Hempel  
In Addi and Cassi's case, we are trying to save the girls from Niemann Pick Type C disease, a fatal cholesterol metabolism disorder that is often referred to as the "Childhood Alzheimer's." There is no cure for NPC and only one ... We know that both Alzheimer's and NPC have tangles in the brain and many other connection points. Why? This is the key question — why would children get and Alzheimer's like condition because of a genetic cholesterol metabolism disorder? ...
View Blog: The Addi and Cassi Fund - Niemann Pick Type C - http://addiandcassi.com/

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View Post: Why Jews have High IQ and disease-prone : Blisstree - Family ...
2 May 2009 by Grace Ibay  
Unfortunately, Ashkenazi Jews are also plague with genetic diseases! One fourth of the population is a carrier of one of several genetic conditions, which include Tay-Sachs Disease, Canavan, Niemann-Pick, Gaucher, ... Considering there is only one human race and millions of years behind human brain evolution, its quite hard to believe that a couple hundreds of years (since Medieval times) have actually enhanced the “brain capacity” of a single ethnic group. ...
View Blog: Genetics & Health - http://www.blisstree.com/geneticsandhealth/

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View Post: MedTRACK ~ メッドトラックの進化の過程と最新情報をUpdate ...
9 Nov 2009 by H.Suzuki  
Bleeding Disorders Information Centre BMC Infectious Diseases BMC MusculoSkeletal Disorders BMJ Publishing Group BRAIN A Journal of Neurology Brain Injury Association of America Bridgehead International British Geriatrics Society .... Niemann Pick Disease group. NJ Department of Health and Senior Services North East Public Health Observatory Northern California Cancer Center Northern Ireland Regional Zoonoses Group Norwegian Institute of Public Health ...
View Blog: MedTRACK ~ メッドトラックの進化の過... - http://medtrackjp.blogspot.com/

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View Post: Sphingomyelinase Deficiency (Niemann-Pick disease) in a Hereford ...
19 Apr 2008 by Saunders, GK, Wenger, DA  
A 5-month-old Hereford calf with neurologic disease was euthanatized, and a necropsy was done. No gross lesions were seen in the brain. Microscopically, neurons throughout the brain and spinal cord had distended, foamy vacuolated cytoplasm. ... An enzyme analysis of a liver extract was performed to confirm the diagnosis of Niemann-Pick disease. A 0.1-g sample of liver was homogenized in 10 volumes of distilled water using a ground glass homogenizer. ...
View Blog: Veterinary Pathology recent issues - http://www.vetpathology.org/

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View Post: Highly variable neural involvement in sphingomyelinase-deficient ...
14 Mar 2007 by Mihaylova, V., Hantke, J., Sinigerska,...  
1Department of Neurology, 2National Genetic Laboratory, and, 3Department of Pediatrics, Medical University, Sofia, Bulgaria, 4Centre for Medical Research and Western Australian Institute for Medical Research, The University of Western ... Niemann–Pick disease (NPD), an autosomal recessive disorder resulting from mutations in the sphingomyelin phosphodiesterase 1 (SMPD1) gene, is subdivided into the acute, lethal neuronopathic type A, and the chronic visceral type B, ...
View Blog: Brain - Advance Access - http://brain.oxfordjournals.org/

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View Post: Study of Pulmonary Complications in Pediatric Patients With ...
2 Jun 2000
I cell disease. Niemann-Pick disease. Wolman disease adrenoleukodystrophy disease-related problem/condition fucosidosis genetic diseases and dysmorphic syndromes globoid cell leukodystrophy inborn errors of metabolism, mannosidosis ... Pick Disease of the Brain Sphingolipidoses Adrenal Gland Diseases Brain Diseases Mucinoses Hereditary Central Nervous System Demyelinating Diseases Metabolism, Inborn Errors Mucopolysaccharidoses Heredodegenerative Disorders, Nervous System ...
View Blog: ClinicalTrials.gov: ALL - http://www.clinicaltrials.gov/ct2/results/rss.xml

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View Post: A contemptible pseudoscientific scam : Pharyngula
19 Nov 2009
which describes the link between Ashkenazi intelligence and their susceptibility to certain genetic disorders... it cites a report in the Journal of Biosocial Science that "Ashkenazim do better than average on IQ tests, scoring some * 12-15 ... The downside is susceptibility to Tay-Sachs, Gaucher's disease and Niemann-Pick - and some other diseases of the mind and the body. Not mentioned is Jewish susceptibility to some of the other diseases, i.e. Cystic Fibrosis, ...
View Blog: Pharyngula - http://scienceblogs.com/pharyngula/

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View Post: Not your grandmother's disease : Dementia in the very young ...
16 Sep 2009 by susanc  
EmpowHer's Encyclopedia describes dementia as "the name given to a group of neurological disorders that progressively deteriorate the ability of the brain to function normally. ... Her dementia is considered similar to Niemann-Pick Disease Type C which is seen in children around the ages of 4 to 10 and shows symptoms similar to dementia. There are currently about 500 children worldwide with Niemann-Pick Type C but experts believe the numbers to be a lot higher, ...
View Blog: EmpowHer.com - Site Activity Feed - http://www.empowher.com/

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View Post: Endosomal Accumulation of Toll-Like Receptor 4 Causes Constitutive ...
21 Feb 2007 by Suzuki, M., Sugimoto, Y., Ohsaki, Y., Ueno,...  
Niemann–Pick disease type C (NPC) is an inherited lipid storage disorder caused by mutations in NPC1 or NPC2 genes. Loss of function of either protein results in the endosomal accumulation of cholesterol and other lipids, ... In the NPC1–/– mouse brain, glial cells expressed TLR4 and IL-6, whereas both glial and neuronal cells expressed STATs. Genetic deletion of TLR4 in NPC1–/– mice reduced IL-6 secretion by cultured fibroblasts but failed to alter STAT levels or glial ...
View Blog: J. Neurosci.: Most-Read Full-Text Articles - http://www.jneurosci.org/

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