Recent Blog Posts

View Post: Cardiology Medical News about Stroke Secondary Prevention
30 Oct 2009
Prasugrel, a new thienopyridine derivative, more quickly and consistently inhibits platelets than clopidogrel. In stroke patients, prasugrel may be associated with a higher risk of brain hemorrhage, so it may not be indicated when there ...
View Blog: Clinical Pharmacology News - http://www.mdlinx.com/HeartLinx/news.cfm/newspage/1/spec_id/2/subspe...

---

View Post: clopidogrel added to aspirin - Pharmacy Forum UK
4 Nov 2009 by star21  
Warfarin is recommended for most patients. Aspirin alone only for very low-risk patients. Aspirin + clopidogrel might be suitable for patients considered to be at high risk of stroke if there are definite contraindications to warfarin. ...
View Blog: Pharmacy Forum UK - http://www.pharmacy-forum.co.uk/

---

View Post: Medco launches 14000 patient head-to-head observational comparison ...
20 Oct 2009 by Larry Husten  
... is designed to assess whether clopidogrel given to patients who are CYP2C19 extensive metabolizers is noninferior to prasugrel on the composite primary endpoint of CV death, nonfatal MI, or nonfatal stroke. ...
View Blog: CardioBrief - http://cardiobrief.org/

---

View Post: BMJ Group blogs: Heart JournalScan » Blog Archive » Clopidogrel ...
21 Jun 2009 by Alistair Lindsay  
The difference was predominantly due to a reduction in the rate of stroke with clopidogrel – stroke occurred in 296 patients in the dual anti-platelet therapy arm (2.4%/year) versus 408 placebo patients (3.3%/year), (RR 0.72, ...
View Blog: Heart JournalScan - http://blogs.bmj.com/heart-journalscan/

---

View Post: Dabigatran vs. warfarin for prevention of stroke in atrial ...
27 Oct 2009 by bowersc  
In the ACTIVE A study (see Blog) clopidogrel plus aspirin reduced the risk of a vascular composite end point compared with aspirin alone in people with AF who were at increased risk of stroke, and for whom warfarin-like drugs were ...
View Blog: NPCi blog - http://www.npci.org.uk/blog/

---

View Post: Three European Analyses Showed Efient is Cost-Effective Compared ...
25 Oct 2009
the 14.5-month trial period were lower with prasugrel compared with branded clopidogrel by euro 20 per patient in the population of patients who had no history of transient ischemic attack/stroke, weight>=60kg and were <75 years-old due ...
View Blog: Flensburg online - http://www.flensburg-online.de/blog/

---

View Post: Aspirin to Prevent Cardiovascular Disease: The Association of ...
16 Mar 2009 by Steinhubl, SR, Bhatt, DL, Brennan, DM,...  
Intervention: Clopidogrel, 75 mg/d, or placebo, with aspirin, 75 to 162 mg/d, as selected by the investigators. Measurements: Incidence of the composite outcome of myocardial infarction, stroke, or cardiovascular death (efficacy end ...
View Blog: ANN INTERN MED: Most-Read Full-Text Articles - http://www.annals.org/

---

View Post: Press Release: Prasugrel Significantly Reduced New or Recurrent ...
2 Sep 2008
The primary endpoint of the study was to compare the effects of prasugrel to clopidogrel on the combined incidence of cardiovascular death, non-fatal heart attack and non-fatal stroke during a median period of at least 12 months ...
View Blog: ThaiPR.net - Other News - http://www.thaipr.net/

---

View Post: Pharmacodynamic effect and clinical efficacy of clopidogrel and ...
1 Sep 2009
Overall, no significant interaction existed between PPI use, use of clopidogrel or prasugrel, and risk of the primary endpoint of cardiovascular death, myocardial infarction, or stroke. Prasugrel was consistently more effective than ...
View Blog: NeLM - News - http://www.nelm.nhs.uk/en/NeLM-Area/News/

---