Recent Blog Posts

View Post: Cystic Fibrosis Clinical Trial: Building Adherence to Live With ...
12 Nov 2009
Building Adherence to Live With And Navigate my Cystic Fibrosis (CF) Experience. Our research group and others have found that patient-reported adherence to all aspects of the regimen is suboptimal and objective measures suggest even ... Prescribed an inhaled mucolytic, inhaled antibiotic therapy, chronic macrolide therapy and/or hypertonic saline therapy for the previous 12 months. 4. Scheduled for a regular visit at either the pediatric or the adult CF clinic at Johns ...
View Blog: Clinical Trials Updates During the Last 7 Days - http://clinicaltrialsfeeds.org/clinical-trials/r...

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View Post: Respiratory Research
Full text
Macrorheology of cystic ... ...
View Blog: Broughton-Head VJ, Smith JR, Shur J, Shute JK: Actin limits enhancement of nanoparticle diffusion through cystic fibrosis sputum by mucolytics. Pulm Pharmacol Ther 2007, 20:708-717. PubMed Abstract

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View Post: actin limits enhancement of nanoparticle diffusion through cystic ...
9 Oct 2007
the secretions in the cystic fibrosis (cf) airways contains high concentrations of polymers, including the respiratory mucins and varying amounts of dna and actin, the debris of an aggressive neutrophilic inflammatory response to ...
View Blog: pulmonologylinx News - http://www.mdlinx.com/PulmonologyLinx/news.cfm?subspec_id=0

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View Post: usmle preparation: Sinusitis
22 Nov 2009 by asghar  
Rhinosinusitis is more common in individuals with congenital defects that affect humoral immunity and ciliary motility, in those with cystic fibrosis, and in persons with AIDS. .... Standard nonantimicrobial treatment options include topical steroids, topical and/or oral decongestants, mucolytics, and intranasal saline spray. A recent meta-analysis of 4 double-blind, placebo-controlled trials of intranasal corticosteroid treatment in acute rhinosinusitis supports its use ...
View Blog: usmle preparation - http://ticpuny.blogspot.com/

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View Post: NHS Evidence Annual Evidence Update on Cystic Fibrosis: 11-15 May ...
8 May 2009
An update of the evidence on cystic fibrosis is available from NHS Evidence and will also include a number of invited commentaries highlighting the key developments in recent years. About this library entry. Category: 3.7 Mucolytics ...
View Blog: NeLM - News - http://www.nelm.nhs.uk/en/NeLM-Area/News/

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View Post: Does nebulized hypertonic saline improve outcomes in patients with ...
5 Oct 2009 by Amy  
Inclusion: Controlled trials compared hypertonic saline to placebo or other mucolytic therapy, for any duration or dose regimen in people with CF (any age or disease severity). Results: 1 double-blind, trial (n=164) with ... Flume PA, Cystic Fibrosis Foundation, Pulmonary Therapies Committee, et al. Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med. 2007; 176(10):957-69. See Hypertonic Saline section for ...
View Blog: Clinical Information - http://healthlibrary.emory.edu/blogs/clininfo/

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View Post: The Boomer Esiason Foundation - CF News
29 Nov 2009
There is hope for two potential cystic fibrosis cures: gene therapy and ion transport restoration. Most mucolytics in the pipeline try to differentiate from currently available mucolytics by providing a new mechanism of action, ...
View Blog: Boomer Esiason Foundation Cystic Fibrosis News - http://www.esiason.org/article.php

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View Post: recombinant human deoxyribonuclease for cystic fibrosis
25 Apr 2006 by nelm@gstt.nhs.uk  
objectives to determine whether the use of rhdnase in cystic fibrosis is associated with improved mortality and morbidity compared to placebo or other mucolytics and to identify any adverse events associated with its use. ...
View Blog: nelm - Evidence Based Resources (Respiratory) - http://www.nelm.nhs.uk/

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View Post: cystic fibrosis
2 Aug 2008 by Ankita  
mucolytics: mucolytics are medicines that help to thin mucus and make it easier to cough out. they are often prescribed to cystic fibrosis patients to help them clear their airways of the thick, sticky mucus that cf causes. ...
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