Recent Blog Posts

View Post: NEJM -- High-Dose Daunorubicin in Older Patients with Acute ...
23 Sep 2009 by Lowenberg, B., Ossenkoppele, GJ, van Putten,...  
Original Article from The New England Journal of Medicine -- High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia. ... High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia ... Hartmut Döhner, M.D., Alois Gratwohl, M.D., Thomas Pabst, M.D., Gregor Verhoef, M.D., for the Dutch-Belgian Cooperative Trial Group for Hemato-Oncology (HOVON), German AML Study Group (AMLSG), and Swiss Group for Clinical Cancer Research (SAKK) Collaborative Group ...
View Blog: NEJM - Articles - http://content.nejm.org/

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View Post: Daunorubicin Versus Mitoxantrone Versus Idarubicin As Induction ...
6 Nov 2009 by Mandelli, Vignetti, Suciu, Stasi, Petti,...  
... the use of mitoxantrone or idarubicin instead of daunorubicin enhances the long-term efficacy of chemotherapy. Supported in part by Grants No. 2U10-CA11488-23 through 2U10-CA11488-36 from the National Cancer Institute, Bethesda, MD; ...
View Blog: Journal of Clinical Oncology Current Issue - http://jco.ascopubs.org/

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View Post: HIGH DOSE DAUNORUBICIN FOR AML
25 Sep 2009 by Dr. NICK  
Fernandez, MD, from the Moffitt Cancer Center and Research Institute in Tampa, Florida. "The lack of an increase in toxic effects and the benefit in overall survival strongly argue for incorporating high-dose daunorubicin into the ...
View Blog: CANCER AND IMPORTANT MEDICAL NEWS - http://cancerology.blogspot.com/

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View Post: Blood Cancers
24 Nov 2009 by Liz  
I answer: “Ok, Doxorubicin and Daunorubicin. MOA is Mechanism of Action. Those are alkylating agents, a type of chemo. They basically lock the DNA in place so it can't replicate, and it works during all the cell cycles. ...
View Blog: Liz's Medical School Journey - http://lizbaltaro.com/

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View Post: Mapping Genes that Contribute to Daunorubicin-Induced Cytotoxicity ...
1 Jun 2007 by Duan, S., Bleibel, WK, Huang, RS, Shukla,...  
R. S. Huang, S. Duan, E. O. Kistner, W. K. Bleibel, S. M. Delaney, D. L. Fackenthal, S. Das, and M. E. Dolan Genetic Variants Contributing to Daunorubicin-Induced Cytotoxicity Cancer Res., May 1, 2008; 68(9): 3161 - 3168. ...
View Blog: Cancer Research current issue - http://cancerres.aacrjournals.org/

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View Post: Histone Deacetylase Inhibitors Induce a Very Broad, Pleiotropic ...
1 Jun 2009 by Hauswald, S., Duque-Afonso, J., Wagner,...  
Results:MDR1, breast cancer resistance protein (BCRP), and multidrug resistance-associated proteins (MRP) 7 and 8 were induced in a dose- and time-dependent manner as shown by semiquantitative PCR. The pattern of gene induction was cell line specific. ... KG-1a cells treated with phenylbutyrate developed resistance to daunorubicin, mitoxantrone, etoposide, vinblastine, paclitaxel, topotecan, gemcitabine, and 5-fluorouracil; as a result drug-induced apoptosis was impaired. ...
View Blog: Clinical Cancer Research recent issues - http://clincancerres.aacrjournals.org/

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View Post: I Think I Might Have Leukemia But My Family Won't Take Me ...
27 Nov 2009 by admin  
Cancer therapy. Children and adults who've had certain types of chemotherapy and radiation therapy or treatment for other kinds of cancer may have a small, but greater, risk of developing acute lymphocytic leukemia than does the general population. .... Children in the high-risk group may also receive an anthracycline drug such as daunorubicin. Adults with ALL receive a similar combination that usually includes vincristine, a corticosteroid and an anthracycline drug. ...
View Blog: Leukemia Blog - http://www.content101.cn/leukemia/

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View Post: Lebed.biz Alert – Cancer Therapeutics (CTHP)
16 Oct 2009 by admin  
CTHP believes that the four NanoTherapies drugs for possible accelerated market delivery and potential revenue are: Methotrexate, Cytarabine, Fludarabine and Daunorubicin. Cerimide-based drugs and a newly discovered Amplified Photon ...
View Blog: Penny Stock Picks - http://www.thepennystockpicks.com/

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View Post: Acute Lymphoblastic Leukemia (ALL)
20 Oct 2009 by admin  
Chemotherapy – Chemotherapy employs the use of cancer-combatant (cytotoxic) drugs for obliterating leukemia cells by interrupting their production. The drugs flow through the body after being intravenously administered. ...
View Blog: Just Cancer - http://www.justcancer.org/

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View Post: Obesity hinders treatment in pediatric leukemia - Cancer Network
29 Oct 2009
Obesity may contribute to chemotherapy resistance and increasing relapse rates among children with leukemia, an animal study in Cancer Research (online, September 22, 2009) suggests. ... MD, PhD, and colleagues developed a mouse model of obesity and leukemia for which they cultured fat and leukemia cells together, and treated the leukemia cells with traditional chemotherapy drugs used in children: vincristine, nilotinib (Tasigna), daunorubicin, and dexamethasone. ...
View Blog: Cancer Network - http://www.cancernetwork.com/

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