Recent Blog Posts

View Post: Daunorubicin Versus Mitoxantrone Versus Idarubicin As Induction ...
6 Nov 2009 by Mandelli, Vignetti, Suciu, Stasi, Petti,...  
Patients and Methods We randomly assigned 2157 patients (age range, 15 to 60 years) to receive intensive induction-consolidation chemotherapy containing either daunorubicin, idarubicin, or mitoxantrone. ...
View Blog: Journal of Clinical Oncology Current Issue - http://jco.ascopubs.org/

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View Post: HIGH DOSE DAUNORUBICIN FOR AML
25 Sep 2009 by Dr. NICK  
September 24, 2009 — High-dose daunorubicin produced a higher rate of remission than the standard dose in patients with acute myeloid leukemia (AML), according to results from 2 large trials published in the September 24 issue of the ...
View Blog: CANCER AND IMPORTANT MEDICAL NEWS - http://cancerology.blogspot.com/

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View Post: High-dose daunorubicin in older patients with acute myeloid leukemia.
25 Sep 2009 by Löwenberg B, Ossenkoppele GJ, van Putten...  
Daunorubicin is a cornerstone of the induction regimen, but the optimal dose is unknown. In older patients, it is usual to give daunorubicin at a dose of 45 to 50 mg per square meter of body-surface area. METHODS: Patients in whom AML ...
View Blog: JournalFeeds - http://journalfeeds.com/

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View Post: Daunorubicin for acute myeloid leukemia
24 Sep 2009
... Belgium, Germany and Switzerland -- studied almost 1500 patients and independently reported higher rates of complete remission and overall survival in those who received high doses of the chemo drug daunorubicin, compared to those ...
View Blog: Current R&D of Pharmaceutical - http://www.cradop.com/component/content/frontpage.html

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View Post: Leukemia Drug in High Dose Helps Survival
25 Sep 2009 by admin  
The lack of an increase in toxic effects and the benefit in overall survival strongly argue for incorporating high-dose daunorubicin into the initial treatment of younger patients with AML, at least for those with favorable- and ...
View Blog: Motherwiz.com - The home of Parenting and Babytalk - http://motherwiz.com/

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View Post: Mapping Daunorubicin-binding Sites in the ATP-binding Cassette ...
8 May 2009 by Smriti, , Zou, P., Mchaourab, HS  
In this study, we have mapped residues proximal to the daunorubicin (DNR)-binding site in MsbA using site-specific, ATP-dependent quenching of DNR intrinsic fluorescence by spin labels. In the nucleotide-free MsbA intermediate, ...
View Blog: Journal of Biological Chemistry current issue - http://www.jbc.org/

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