Recent Blog Posts

View Post: Scrip News - XenoPort/Astellas's gabapentin prodrug filed for ...
20 Nov 2009
Astellas has submitted an approval application in Japan for gabapentin enacarbil (ASP8825) for the treatment of restless legs syndrome (RLS). The filing triggers a $5 million milestone payment to the Japanese firm's licensor, XenoPort, ...
View Blog: Scrip News - Home - RSS - http://www.scripnews.com/home/

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View Post: Health Care Renewal: The Editorial that Wasn't: Evidence for ...
16 Nov 2009 by Roy M. Poses MD  
For example, the 2005 Cochrane systematic review regarding the effectiveness of gabapentin for acute and chronic pain concluded that it is effective on the basis of published findings and should now be updated with the inclusion of ...
View Blog: Health Care Renewal - http://hcrenewal.blogspot.com/

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View Post: Gabapentin in carpal tunnel patients: A consideration Wiwanitkit V ...
21 Nov 2009 by Wiwanitkit Viroj  
To the Editor: I read the publication by Erdemoglu et al., with great interest. The authors reported the efficacy of gabapentin in patients with carpal tunnel syndrome and concluded that gabapentin is useful in patients who are ...
View Blog: Table of Contents : Neurology India : 2009 - 57(5) - http://www.neurologyindia.com/currentissue.asp

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View Post: Published evidence for off-label gabapentin uses is incomplete - NeLM
12 Nov 2009
The authors of this paper report an analysis of the outcomes reported in published papers describing unlicensed (off-label) uses of gabapentin, using internal company documents made available as a result of US litigation. ...
View Blog: NeLM - News - http://www.nelm.nhs.uk/en/NeLM-Area/News/

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View Post: Selective outcome reporting identified in industry-sponsored ...
23 Nov 2009 by bowersc  
A study has found evidence of selective outcome reporting in industry-sponsored reports of randomised trials of off-label use of gabapentin. For eight of the twelve reported trials, the primary outcome differed from that described in ...
View Blog: NPCi blog - http://www.npci.org.uk/blog/

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View Post: Japanese filing of gabapentin enacarbil for RLS triggers $5 ...
20 Nov 2009
Japanese drug major Astellas Pharma has filed a New Drug Application with the Pharmaceuticals and Medical Device Agency (PMDA) in Japan for ASP8825 (gabapentin enacarbil), also known as XP13512, as a potential treatment for restless ...
View Blog: thepharmaletter.com - http://www.thepharmaletter.com/

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View Post: Cell - Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin ...
15 Nov 2009
Here, we identify the neuronal thrombospondin receptor involved in CNS synapse formation as α2δ-1, the receptor for the anti-epileptic and analgesic drug gabapentin. We show that the VWF-A domain of α2δ-1 interacts with the epidermal ...
View Blog: CELL - http://www.cell.com/mostread

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