Recent Blog Posts

View Post: Developmental renin expression in mice with a defective renin ...
30 Oct 2009 by Machura, K., Steppan, D., Neubauer, B.,...  
During nephrogenesis, renin expression shifts from the vessel walls of interlobular arteries to the terminal portions of afferent arterioles in a wavelike pattern. Since the mechanisms responsible for the developmental deactivation of ...
View Blog: AJP: Renal Physiology recent issues - http://ajprenal.physiology.org/

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View Post: Vitae Pharmaceuticals, Inc. to Reacquire Full Rights to Renin ...
21 Oct 2008
“We are excited to regain full ownership and control of our promising renin program as we prepare to enter our lead compound into clinical trials in 2009,” said Jeffrey Hatfield, Chief Executive Officer of Vitae. “Renin continues to be ...
View Blog: BioSpace.com Featured News and Stories - http://www.biospace.com/

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View Post: The Effect of Direct Renin Inhibition on Renal Hemodynamic ...
4 Nov 2009 by Cherney, DZI, Lai, V., Scholey, JW, Miller,...  
The Effect of Direct Renin Inhibition on Renal Hemodynamic Function, Arterial Stiffness and Endothelial Function in Humans with Uncomplicated Type 1 Diabetes Mellitus: A Pilot Study ...
View Blog: Diabetes Care Journal publish ahead of... - http://care.diabetesjournals.org/

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View Post: Plasma renin activity associated with cardiovascular events and ...
16 Nov 2009
Patients with elevated baseline plasma renin activity levels had a twofold increased risk of total or cardiovascular mortality compared with those with low levels, and the strength of the association persisted after multiple adjustments ...
View Blog: theHeart.org - Heart failure - http://www.theheart.org/condition/heart-failure.do

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View Post: BIO-SYNTHESIS - Custom Antibody Custom Peptide Synthesis Custom ...
31 Oct 2009 by Jessica  
Renin inhibitors represent an alternative to angiotensin-converting enzyme inhibitors (ACEI) for the treatment of hypertension. They inhibit the renin-angiotensin system at its first and rate limiting step, the renin-angiotensinogen ...
View Blog: BIO-SYNTHESIS - Custom Antibody Custom... - http://bio-synthesis.blogspot.com/

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View Post: Renin-Angiotensin System Gene Polymorphisms and Atrial ...
4 Feb 2008
Objectives: To test the association between renin-angiotensin system gene variants and atrial fibrillation (AF) using a regression approach. Methods: A total of 1236 consecutive patients (227 with AF and 1009 with normal sinus rhythm as ...
View Blog: American Journal of Nephrology : Last 20 articles - http://content.karger.com/

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View Post: Inhibition of calcineurin phosphatase promotes exocytosis of renin ...
13 Nov 2009 by Madsen K, Friis UG, Gooch JL, Hansen PB,...  
To examine the role of the calcium/calmodulin-dependent phosphatase calcineurin in regulation of renin release, we assayed exocytosis using whole-cell patch clamp of single juxtaglomerular cells in culture. The calcineurin inhibitor ...
View Blog: Research Papers, Journals, Pubmed - http://pubmeddy.com/

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View Post: Impact of renin-angiotensin-aldosterone blockade by angiotensin ...
9 Nov 2009 by Kiski, D., Stepper, W., Brand, E., Breithardt,...  
Background. After exposure to contrast medium (CM), about 10% of patients will develop contrast medium-induced nephropathy (CIN), with severe consequences for their prognosis. Although numerous studies evaluated risk factors for CIN ...
View Blog: Nephrology Dialysis Transplantation - Advance... - http://ndt.oxfordjournals.org/

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View Post: Combined renin-angiotensin-aldosterone system inhibition in ...
11 Nov 2009 by Gradman AH, Papademetriou V  
In addition to lowering blood pressure, blockade of the renin-angiotensin-aldosterone system can reduce the negative effects of chronic renin-angiotensin-aldosterone system activation on the progression of HF. This review discusses the ...
View Blog: JournalFeeds - http://journalfeeds.com/

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View Post: Hypertension Clinical Trial: Genetic Mechanisms in Human ...
5 Nov 2009
Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study. The purpose of this study is to develop an approach to provide personalized medicine to individuals who have hypertension (high blood ...
View Blog: Clinical Trials Updates During the Last 7 Days - http://clinicaltrialsfeeds.org/clinical-trials/r...

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