Recent Blog Posts

View Post: Serum aldosterone is correlated positively to parathyroid hormone ...
1 Dec 2009 by Laurent Brunaud, Adeline Germain, Rasa...  
As there is clear evidence of the independent role of aldosterone on the cardiovascular system, the aim of this study was to evaluate aldosterone levels in patients with primary hyperparathyroidism.Methods: A prospective study of 134 ...
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View Post: Aldosterone Promotes Fibronectin Synthesis in Rat Mesangial Cells ...
4 Nov 2009
Then, after exposure to aldosterone, the NHE1 protein abundance was found increased in rat mesangial cells. Aldosterone treatment markedly increased the fibronectin level, which can be reduced by PD98059, spironolactone and shRNA-NHE1. ...
View Blog: American Journal of Nephrology : Last 20 articles - http://content.karger.com/

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View Post: Within-Patient Reproducibility of the Aldosterone:Renin Ratio in ...
23 Nov 2009 by Rossi, G. P., Seccia, T. M., Palumbo, G.,...  
Abstract—The plasma aldosterone concentration:renin ratio (ARR) is widely used for the screening of primary aldosteronism, but its reproducibility is unknown. We, therefore, investigated the within-patient reproducibility of the ARR in ...
View Blog: Hypertension On-line First - http://hyper.ahajournals.org/

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View Post: Activation of local aldosterone system within podocytes is ...
30 Oct 2009 by Lee, SH, Yoo, T.-H., Nam, B.-Y., Kim, DK,...  
Previous studies have shown that mineralocorticoid receptor (MCR) blocker reduces proteinuria in diabetic nephropathy (DN), but the role of aldosterone in podocyte injury has never been explored in DN. This study was undertaken to ...
View Blog: AJP: Renal Physiology recent issues - http://ajprenal.physiology.org/

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View Post: Narrative Review: The Emerging Clinical Implications of the Role ...
1 Jun 2009 by Sowers, JR, Whaley-Connell, A., Epstein, M.  
Emerging evidence supports a paradigm shift in our understanding of the renin–angiotensin–aldosterone system and in aldosterone's ability to promote insulin resistance and participate in the pathogenesis of the metabolic syndrome and ...
View Blog: ANN INTERN MED: Most-Read Full-Text Articles - http://www.annals.org/

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View Post: USA and Europe different in aldosterone antagonists use in heart ...
21 Oct 2009 by News  
A study published today in JAMA (October 21) by Nancy M. Albert and colleagues, exploring aldosterone antagonist usage among US patients hospitalised with heart failure, found that only one-third of patients meeting current US Clinical ...
View Blog: Science Codex - Science news, science articles,... - http://www.sciencecodex.com/

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View Post: ESC Press Statement: USA and Europe different in the use of ...
21 Oct 2009
ESC Guidelines for aldosterone antagonist use in heart failure, Prof Dickstein explained, are based around a single study - the RALES trial, where patients with severe heart failure were randomised to spironolactone or placebo (2). ...
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View Post: Aldosterone Modulates Steroid Receptor Binding to the Endothelin-1 ...
23 Oct 2009 by Stow, LR, Gumz, ML, Lynch, IJ, Greenlee,...  
Aldosterone and endothelin-1 (ET-1) act on collecting duct cells of the kidney and are important regulators of renal sodium transport and cardiovascular physiology. We recently identified the ET-1 gene (edn1) as a novel ...
View Blog: Journal of Biological Chemistry current issue - http://www.jbc.org/

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View Post: Hypertension Clinical Trial: Genetic Mechanisms in Human ...
5 Nov 2009
Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study. The purpose of this study is to develop an approach to provide personalized medicine to individuals who have hypertension (high blood ...
View Blog: Clinical Trials Updates During the Last 7 Days - http://clinicaltrialsfeeds.org/clinical-trials/r...

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